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NDB ID: 8E8H    PDB ID: 8E8H     NAKB: 8E8H 


Title:

HUMAN DNA POLYMERASE ETA-DNA-RU-ENDED PRIMER TERNARY MISMATCH COMPLEX:REACTION WITH 10 MM MN2+ FOR 300S

Molecular Description:

Deposited:

2022-08-25

Released:

2023-02-01

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Chang, C., Lee Luo, C., Eleraky, S., Lin, A., Zhou, G., Gao, Y.
Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. 
J.Biol.Chem., 299, pp. 102938 - 102938, 2023.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 98.06   b = 98.06   c = 81.26 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2057 for 24687 reflections in the resolution range 32.1 to 2.13 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)