CRYSTAL STRUCTURE ANALYSIS OF THE A-DNA DECAMER GCGT-2'OMEA-AU-ACGC, WITH INCORPORATED 2'-O-METHYLATED-ADENOSINE (2'OMEA) AND ARABINO-URIDINE (AU)
A DOUBLE HELIX
Chain A, B
No Protein Sequence Found
Li, F., Sarkhel, S., Wilds, C.J., Wawrzak, Z., Prakash, T.P., Manoharan, M., Egli, M.
2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45, pp. 4141 - 4152, 2006.
P 21 21 21
a = 32.277 b = 32.469 c = 66.749 (Ångstroms)
α = 90.0 β = 90.0 γ = 90.0 (degrees)
The structure was refined using the REFMAC 5.2.0005 program. The R value is 0.15856 for 21724 reflections in the resolution range 33.37 to 1.19 Ångstroms with Fobs > 0.0 sigma(Fobs) and with I > 0.0 sigma(I)
Biological Assembly coordinates (pdb format) 1