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NDB ID: AH0001    PDB ID: 404D 


Title:

CRYSTAL STRUCTURE OF THE RNA/DNA HYBRID R(GAAGAGAAGC). D(GCTTCTCTTC)

Molecular Description:

5'-R(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3' 5'-D(*GP*CP*TP*TP*CP*TP*CP*TP*TP*C)-3'

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Conn, G.L., Brown, T., Leonard, G.A.
The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC). d(GCTTCTCTTC) shows significant differences to that found in solution. 
Nucleic Acids Res., 27, pp. 555 - 561, 1999.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 25.72   b = 45.55   c = 47.81 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.181 for 1867 reflections in the resolution range 20.0 to 2.5 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)