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NDB ID: AH0002    PDB ID: 410D 


Title:

DUPLEX [5'-D(GCGTA+TACGC)]2 WITH INCORPORATED 2'-O-ETHOXYMETHYLENE RIBONUCLEOSIDE

Molecular Description:

5'-D(*GP*CP*GP*TP*AP*(T38)P*AP*CP*GP*C)-3'

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Tereshko, V., Portmann, S., Tay, E.C., Martin, P., Natt, F., Altmann, K.H., Egli, M.
Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues. 
Biochemistry, 37, pp. 10626 - 10634, 1998.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 24.62   b = 44.08   c = 46.18 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the X-PLOR 3.851 program. The R value is 0.159 for 6414 reflections in the resolution range 8.0 to 1.6 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)