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NDB ID: AH0010    PDB ID: 1EFO 


Title:

CRYSTAL STRUCTURE OF AN ADENINE BULGE IN THE RNA CHAIN OF A DNA/RNA HYBRID, D(CTCCTCTTC)/R(GAAGAGAGAG)

Molecular Description:

5'-D(*CP*TP*CP*CP*TP*CP*TP*TP*C)-3'
5'-R(*GP*AP*AP*GP*AP*GP*AP*GP*AP*G)-3'

Structural Keywords:

A DOUBLE HELIX, FLIPPED-OUT BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Sudarsanakumar, C., Xiong, Y., Sundaralingam, M.
Crystal structure of an adenine bulge in the RNA chain of a DNA.RNA hybrid, d(CTCCTCTTC).r(gaagagagag). 
J.Mol.Biol., 299, pp. 103 - 112, 2000.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 2 2 2

Cell Constants:

a = 46.66   b = 47.61   c = 54.04 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.199 for 2486 reflections in the resolution range 10.0 to 2.3 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  1.0 sigma(I)