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NDB ID: AH0019    PDB ID: 1JB8 


Title:

THE CRYSTAL STRUCTURE OF AN RNA/DNA HYBRID REVEALS NOVEL INTERMOLECULAR INTERCALATION

Molecular Description:

5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3'
5'-D(*CP*TP*TP*TP*TP*CP*TP*TP*TP*G)-3'

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Han, G.W., Kopka, M.L., Langs, D., Sawaya, M.R., Dickerson, R.E.
Crystal structure of an RNADNA hybrid reveals intermolecular intercalation: Dimer formation by base-pair swapping 
Proc.Natl.Acad.Sci.USA, 100, pp. 9214 - 9219, 2003.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 2 2 2

Cell Constants:

a = 45.234   b = 46.78   c = 56.56 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 2171 reflections in the resolution range 10.0 to 2.38 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)