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NDB ID: AR0023    PDB ID: 1CSL 


Title:

CRYSTAL STRUCTURE OF THE RRE HIGH AFFINITY SITE

Molecular Description:

5'-R(*AP*AP*CP*GP*GP*GP*CP*GP*CP*AP*GP*AP*A)-3'
5'-R(*UP*CP*UP*GP*AP*CP*GP*GP* UP*AP*CP*GP*UP*UP*U)-3'

Structural Keywords:

A DOUBLE HELIX, FLIPPED-OUT BASES, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Ippolito, J.A., Steitz, T.A.
The structure of the HIV-1 RRE high affinity rev binding site at 1.6 A resolution. 
J.Mol.Biol., 295, pp. 711 - 717, 2000.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 74.5   b = 24.3   c = 46.1 (Ångstroms)

α = 90.0   β = 116.7   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.211 for 9640 reflections in the resolution range 15.0 to 1.6 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)