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NDB ID: AR0062    PDB ID: 1ZEV 


Title:

CRYSTAL STRUCTURE OF A PATHOGENIC RNA: CUG REPEATS

Molecular Description:

5'-R(*CP*UP*GP*CP*UP*GP*CP*UP*GP*CP*UP*GP*CP*UP*GP*CP*UP*G)-3'

Deposited:

2005-04-19

Released:

2005-10-25

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Mooers, B.H., Logue, J.S., Berglund, J.A.
The structural basis of myotonic dystrophy from the crystal structure of CUG repeats. 
Proc.Natl.Acad.Sci.Usa, 102, pp. 16626 - 16631, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

H 3

Cell Constants:

a = 39.102   b = 39.102   c = 141.277 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.224 for 9965 reflections in the resolution range 19.55 to 1.58 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)