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NDB ID: AR0071    PDB ID: 2NOK 


Title:

CRYSTAL STRUCTURE OF AN RNA DOMAIN FROM HEPATITIS C VIRUS.

Molecular Description:

5'-R(*CP*GP*GP*AP*GP*GP*AP*AP*CP*UP*AP*CP*UP*GP*UP*CP*UP*UP*CP*AP*CP*GP*CP*C)-3'

Structural Keywords:

A DOUBLE HELIX, BULGES, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Dibrov, S.M., Johnston-Cox, H., Weng, Y.H., Hermann, T.
Functional architecture of HCV IRES domain II stabilized by divalent metal ions in the crystal and in solution. 
Angew.Chem.Int.Ed.Engl., 46, pp. 226 - 229, 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 62.098   b = 65.351   c = 92.4 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.2.0019 program. The R value is 0.25932 for 7156 reflections in the resolution range 20.0 to 3.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)