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NDB ID: BD0091    PDB ID: 2FIH 


Title:

CRYSTAL STRUCTURE ANALYSIS OF THE B-DNA DODECAMER CGCGAA-AU-TCGCG, WITH INCORPORATED ARABINO-URIDINE (AU)

Molecular Description:

5'-D(*CP*GP*CP*GP*AP*AP*(UAR)P*TP*CP*GP*CP*G)-3'

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Li, F., Sarkhel, S., Wilds, C.J., Wawrzak, Z., Prakash, T.P., Manoharan, M., Egli, M.
2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H. 
Biochemistry, 45, pp. 4141 - 4152, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 25.474   b = 39.757   c = 65.345 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the SHELXL-97 program. The R value is 0.191 for 0 reflections in the resolution range 50.0 to 1.13 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)