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NDB ID: DR0014    PDB ID: 2A04 


Title:

MOLECULAR RECOGNITION OF RNA BY NEOMYCIN AND A RESTRICTED NEOMYCIN DERIVATIVE

Molecular Description:

5'-R(*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*GP*G)-3'/ 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*C)-3'
NEOMYCIN

Structural Keywords:

A DOUBLE HELIX, BULGES, FLIPPED-OUT BASES, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Zhao, F., Zhao, Q., Blount, K.F., Han, Q., Tor, Y., Hermann, T.
Molecular recognition of RNA by neomycin and a restricted neomycin derivative 
Angew.Chem.Int.Ed.Engl., 44, pp. 5329 - 5334, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 49.8   b = 49.9   c = 144.6 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.0 program. The R value is 0.2976 for 6650 reflections in the resolution range 8.0 to 2.95 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)