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NDB ID: DR0016    PDB ID: 2ET4 


Title:

COMPLEX BETWEEN NEOMYCIN B AND THE 16S-RRNA A-SITE

Molecular Description:

5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'

Structural Keywords:

A DOUBLE HELIX, BULGES, FLIPPED-OUT BASES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Francois, B., Russell, R.J., Murray, J.B., Aboul-ela, F., Masquida, B., Vicens, Q., Westhof, E.
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding. 
Nucleic Acids Res., 33, pp. 5677 - 5690, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 33.22   b = 45.95   c = 93.81 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.1 program. The R value is 0.2085 for 5398 reflections in the resolution range 30.0 to 2.4 Ångstroms with Fobs >  1.5 sigma(Fobs) and with I >  0.0 sigma(I)