NDB ID: DR0019    PDB ID: 2BE0 

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Title:

COMPLEX BETWEEN PAROMOMYCIN DERIVATIVE JS5-39 AND THE 16S-RRNA A-SITE.

Molecular Description:

5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'
2""-O-[N-(3-(AMINOMETHYL)-PYRIDINE)-2-AMINOETHYL]PAROMOMYCIN

Deposited:

2005-10-21

Released:

2005-12-20

Structural Keywords:

A DOUBLE HELIX, FLIPPED-OUT BASES, BULGES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Francois, B., Szychowski, J., Adhikari, S.S., Pachamuthu, K., Swayze, E.E., Griffey, R.H., Migawa, M.T., Westhof, E., Hanessian, S.
Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site 
ANGEW.CHEM.INT.ED.ENGL., 43, pp. 6735 - 6738, 2004.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41

Cell Constants:

a = 39.141   b = 39.141   c = 99.14 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 4291 reflections in the resolution range 30.0 to 2.63 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)

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Asymmetric Unit coordinates (pdb format, Unix compressed(.gz))

Asymmetric Unit coordinates (cif format, Unix compressed(.gz))

Biological Assembly coordinates (pdb format) 1

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

XML | Complete with coordinates (xml format, GNU compressed(.gz))

XML | Coordinates only (xml format, GNU compressed(.gz))

XML | Header only (xml format, GNU compressed(.gz))