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NDB ID: DR0021    PDB ID: 2ESI 


Title:

COMPLEX BETWEEN KANAMYCIN A AND THE 16S-RRNA A SITE.

Molecular Description:

5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'
KANAMYCIN A

Structural Keywords:

A DOUBLE HELIX, FLIPPED-OUT BASES, BULGES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Francois, B., Russel, R.J.M., Murray, J.B., Aboul-ela, F., Masquida, B., Vicens, Q., Westhof, E.
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding 
Nucleic Acids Res., 33, pp. 5677 - 5790, 2005.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 47.38   b = 32.73   c = 52.7 (Ångstroms)

α = 90.0   β = 107.38   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.1 program. The R value is 0.0 for 2454 reflections in the resolution range 30.0 to 3.0 Ångstroms with Fobs >  1.0 sigma(Fobs) and with I >  0.0 sigma(I)