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NDB ID: DR0024    PDB ID: 2FCY 


Title:

HIV-1 DIS KISSING-LOOP IN COMPLEX WITH NEOMYCIN

Molecular Description:

5'-R(*CP*UP*(5BU)P*GP*CP*UP*GP*AP*AP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3'

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Ennifar, E., Paillart, J.C., Bodlenner, A., Walter, P., Weibel, J.-M., Aubertin, A.-M., Pale, P., Dumas, P., Marquet, R.
Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell. 
Nucleic Acids Res., 34, pp. 2328 - 2339, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 27.105   b = 113.702   c = 96.165 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.1 program. The R value is 0.235 for 7669 reflections in the resolution range 18.22 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)