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NDB ID: DR0028    PDB ID: 2F4T 


Title:

ASITE RNA + DESIGNER ANTIBIOTIC

Molecular Description:

5'-R(*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'

Structural Keywords:

A DOUBLE HELIX, BULGES, FLIPPED-OUT BASES, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Murray, J.B., Meroueh, S.O., Russell, R.J., Lentzen, G., Haddad, J., Mobashery, S.
Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site 
Chem.Biol., 13, pp. 129 - 138, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 45.976   b = 32.926   c = 46.414 (Ångstroms)

α = 90.0   β = 95.62   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.267 for 2735 reflections in the resolution range 15.0 to 3.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)