A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 30-Nov-2016 number of released structures: 8621
Search for released structures

NDB ID: DR0035    PDB ID: 2OE5 


Title:

1.5 A X-RAY CRYSTAL STRUCTURE OF APRAMYCIN COMPLEX WITH RNA FRAGMENT GGCGUCGCUAGUACCG/GGUACUAAAAGUCGCCC CONTAINING THE HUMAN RIBOSOMAL DECODING A SITE: RNA CONSTRUCT WITH 3'-OVERHANG

Molecular Description:

Synthetic RNA fragment containing the human ribosomal decoding A site
apramycin

Structural Keywords:

A DOUBLE HELIX, OVERHANGING BASES, MISMATCHED BASE PAIR, BULGE

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Hermann, T., Tereshko, V., Skripkin, E., Patel, D.J.
Apramycin recognition by the human ribosomal decoding site. 
Blood Cells Mol.Dis., 38, pp. 193 - 198, 2007.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 28.31   b = 36.693   c = 86.679 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5 program. The R value is 0.20006 for 13173 reflections in the resolution range 19.92 to 1.51 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)