CRYSTAL STRUCTURE OF THE BACTERIAL RIBOSOMAL DECODING SITE COMPLEXED WITH AMINOGLYCOSIDE CONTAINING THE L-HABA GROUP
22-mer of the ribosomal decoding site/paromomycin derivative
RH DOUBLE HELIX, LOOPS, HAIRPIN LOOP, FLIPPED-OUT BASES, BULGES
Chain A, B
No Protein Sequence Found
Kondo, J., Pachamuthu, K., Francois, B., Szychowski, J., Hanessian, S., Westhof, E.
Crystal Structure of the Bacterial Ribosomal Decoding Site Complexed with a Synthetic Doubly Functionalized Paromomycin Derivative: a New Specific Binding Mode to an A-Minor Motif Enhances in vitro Antibacterial Activity
Chemmedchem, 2, pp. 1631 - 1638, 2007.
P 21 21 21
a = 35.49 b = 43.02 c = 98.75 (Ångstroms)
α = 90.0 β = 90.0 γ = 90.0 (degrees)
The structure was refined using the CNS program. The R value is 0.0 for 14603 reflections in the resolution range 32.0 to 1.8 Ångstroms with Fobs > 0.0 sigma(Fobs) and with I > 0.0 sigma(I)
Biological Assembly coordinates (pdb format) 1