A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 25-May-2016 number of released structures: 8217
Search for released structures

NDB ID: NA0005    PDB ID: 3HJF 


Title:

CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE E546 MUTANT PROTEIN COMPLEXED WITH DNA GUIDE STRAND AND 15-NT RNA TARGET STRAND

Molecular Description:

Argonaute/DNA/RNA complex

Structural Keywords:

A DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Wang, Y., Juranek, S., Li, H., Sheng, G., Wardle, G.S., Tuschl, T., Patel, D.J.
Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. 
Nature, 461, pp. 754 - 761, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43 21 2

Cell Constants:

a = 111.868   b = 111.868   c = 177.035 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine) program. The R value is 0.205 for 21166 reflections in the resolution range 43.554 to 3.056 Ångstroms with Fobs >  0.09 sigma(Fobs) and with I >  0.0 sigma(I)