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NDB ID: NA0018    PDB ID: 2VQE 

Title:

MODIFIED URIDINES WITH C5-METHYLENE SUBSTITUENTS AT THE FIRST POSITION OF THE TRNA ANTICODON STABILIZE U-G WOBBLE PAIRING DURING DECODING

Molecular Description:

30S RIBOSOMAL PROTEIN S2
30S RIBOSOMAL PROTEIN S3
30S RIBOSOMAL PROTEIN S4
30S RIBOSOMAL PROTEIN S5
30S RIBOSOMAL PROTEIN S6
30S RIBOSOMAL PROTEIN S7
30S RIBOSOMAL PROTEIN S8
30S RIBOSOMAL PROTEIN S9
30S RIBOSOMAL PROTEIN S10
30S RIBOSOMAL PROTEIN S11
30S RIBOSOMAL PROTEIN S12
30S RIBOSOMAL PROTEIN S13
30S RIBOSOMAL PROTEIN S14 TYPE Z
30S RIBOSOMAL PROTEIN S15
30S RIBOSOMAL PROTEIN S16
30S RIBOSOMAL PROTEIN S17
30S RIBOSOMAL PROTEIN S18
30S RIBOSOMAL PROTEIN S19
30S RIBOSOMAL PROTEIN S20
30S RIBOSOMAL PROTEIN THX/RNA Complex
PAROMOMYCIN

Deposited:

2008-03-13

Released:

2008-04-29

Structural Keywords:

SINGLE STRAND, LOOP, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 20 protein sequences

Primary Citation:

Kurata, S., Weixlbaumer, A., Ohtsuki, T., Shimazaki, T., Wada, T., Kirino, Y., Takai, K., Watanabe, K., Ramakrishnan, V., Suzuki, T.
Modified Uridines with C5-Methylene Substituents at the First Position of the tRNA Anticodon Stabilize U.G Wobble Pairing During Decoding. 
J.Biol.Chem., 283, pp. 18801 - , 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 401.998   b = 401.998   c = 175.648 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.257 for 487131 reflections in the resolution range 49.5 to 2.5 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)

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