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NDB ID: NA0065    PDB ID: 3I0W 


Title:

CRYSTAL STRUCTURE OF CLOSTRIDIUM ACETOBUTYLICUM 8-OXOGUANINE GLYCOSYLASE/LYASE IN COMPLEX WITH DSDNA CONTAINING CYTOSINE OPPOSITE TO 8-OXOG

Molecular Description:

8-oxoguanine-DNA-glycosylase (E.C.3.2.2.-
4.2.99.18)/DNA complex

Deposited:

2009-06-25

Released:

2009-09-29

Structural Keywords:

B DOUBLE HELIX, FLIPPED-OUT BASES, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Faucher, F., Wallace, S.S., Doublie, S.
Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase. 
Dna Repair, 8, pp. 1283 - 1289, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 92.4   b = 92.4   c = 191.05 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.195 for 48375 reflections in the resolution range 19.9 to 1.73 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)