NDB ID: NA0106    PDB ID: 3IGL     NAKB(beta): NA0106 

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Title:

DIVERSITY IN DNA RECOGNITION BY P53 REVEALED BY CRYSTAL STRUCTURES WITH HOOGSTEEN BASE PAIRS (P53-DNA COMPLEX 1)

Molecular Description:

Cellular tumor antigen p53/DNA

Deposited:

2009-07-28

Released:

2010-03-31

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Kitayner, M., Rozenberg, H., Rohs, R., Suad, O., Rabinovich, D., Honig, B., Shakked, Z.
Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs 
Nat.Struct.Mol.Biol., 17, pp. 423 - 429, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 137.161   b = 49.841   c = 33.962 (Ångstroms)

α = 90.0   β = 93.96   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.15093 for 19216 reflections in the resolution range 24.92 to 1.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)

Download Data:

Asymmetric Unit coordinates (pdb format, Unix compressed(.gz))

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Biological Assembly coordinates (pdb format) 1

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

XML | Complete with coordinates (xml format, GNU compressed(.gz))

XML | Coordinates only (xml format, GNU compressed(.gz))

XML | Header only (xml format, GNU compressed(.gz))