NDB ID: NA0119    PDB ID: 3HM9 

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Title:

CRYSTAL STRUCTURE OF T. THERMOPHILUS ARGONAUTE COMPLEXED WITH DNA GUIDE STRAND AND 19-NT RNA TARGET STRAND

Molecular Description:

Argonaute

Deposited:

2009-05-28

Released:

2009-10-06

Structural Keywords:

A DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Wang, Y., Juranek, S., Li, H., Sheng, G., Wardle, G.S., Tuschl, T., Patel, D.J.
Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. 
Nature, 461, pp. 754 - 761, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43 21 2

Cell Constants:

a = 111.916   b = 111.916   c = 175.551 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.239 for 17255 reflections in the resolution range 20.0 to 3.3 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)

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Asymmetric Unit coordinates (pdb format, Unix compressed(.gz))

Asymmetric Unit coordinates (cif format, Unix compressed(.gz))

Biological Assembly coordinates (pdb format) 1

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

XML | Complete with coordinates (xml format, GNU compressed(.gz))

XML | Coordinates only (xml format, GNU compressed(.gz))

XML | Header only (xml format, GNU compressed(.gz))