A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 23-Sep-2020 number of released structures: 10967
Search for released structures

NDB ID: NA0131    PDB ID: 3ISC 


Title:

BINARY COMPLEX OF HUMAN DNA POLYMERASE BETA WITH AN ABASIC SITE (THF) IN THE GAPPED DNA

Molecular Description:

DNA polymerase beta (E.C.2.7.7.7
4.2.99.-)

Deposited:

2009-08-25

Released:

2009-09-15

Structural Keywords:

B DOUBLE HELIX, ABASIC SITE IN GAPPED DNA

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Beard, W.A., Shock, D.D., Batra, V.K., Pedersen, L.C., Wilson, S.H.
DNA polymerase beta substrate specificity: side chain modulation of the ""A-rule"". 
J.Biol.Chem., 284, pp. 31680 - 31689, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 54.41   b = 79.3   c = 54.95 (Ångstroms)

α = 90.0   β = 105.8   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.186 for 29317 reflections in the resolution range 21.81 to 2.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)