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NDB ID: NA0138    PDB ID: 3JQ4 


Title:

THE STRUCTURE OF THE COMPLEX OF THE LARGE RIBOSOMAL SUBUNIT FROM D. RADIODURANS WITH THE ANTIBIOTIC LANKACIDIN

Molecular Description:

23S ribosomal RNA/5S ribosomal RNA
lankacidin C complex

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Auerbach, T., Mermershtain, I., Davidovich, C., Bashan, A., Belousoff, M., Wekselman, I., Zimmerman, E., Xiong, L., Klepacki, D., Arakawa, K., Kinashi, H., Mankin, A.S., Yonath, A.
The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics 
Proc.Natl.Acad.Sci.USA, 107, pp. 1983 - 1988, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 2 2 2

Cell Constants:

a = 169.8   b = 410.3   c = 694.4 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.2 program. The R value is 0.268 for 248571 reflections in the resolution range 8.0 to 3.52 Ångstroms with Fobs >  -2.0 sigma(Fobs) and with I >  0.0 sigma(I)