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NDB ID: NA0142    PDB ID: 3A6P 


Title:

CRYSTAL STRUCTURE OF EXPORTIN-5:RANGTP:PRE-MIRNA COMPLEX

Molecular Description:

Exportin-5/13-mer peptide/GTP-binding nuclear protein Ran/RNA

Structural Keywords:

A DOUBLE HELIX, BULGE

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

Okada, C., Yamashita, E., Lee, S.J., Shibata, S., Katahira, J., Nakagawa, A., Yoneda, Y., Tsukihara, T.
A high-resolution structure of the pre-microRNA nuclear export machinery 
Science, 326, pp. 1275 - 1279, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 71.157   b = 304.667   c = 89.23 (Ångstroms)

α = 90.0   β = 110.79   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.2.0019 program. The R value is 0.25061 for 71062 reflections in the resolution range 39.84 to 2.92 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)