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NDB ID: NA0252    PDB ID: 2W8L 


Title:

Y-FAMILY DNA POLYMERASE DPO4 BYPASSING N2-NAPHTHYL-GUANINE ADDUCT IN ANTI ORIENTATION

Molecular Description:

DNA POLYMERASE IV (E.C.2.7.7.7)

Deposited:

2009-01-16

Released:

2009-01-27

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Zhang, H., Eoff, R.L., Kozekov, I.D., Rizzo, C.J., Egli, M., Guengerich, F.P.
Versatility of Y-Family Sulfolobus Solfataricus DNA Polymerase Dpo4 in Translesion Synthesis Past Bulky N2-Alkylguanine Adducts. 
J.Biol.Chem., 284, pp. 3563 - , 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 95.919   b = 103.832   c = 52.493 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.226 for 10584 reflections in the resolution range 29.25 to 3.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)