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NDB ID: NA0268    PDB ID: 1UVI 


Title:

THE STRUCTURAL BASIS FOR RNA SPECIFICITY AND CA2 INHIBITION OF AN RNA-DEPENDENT RNA POLYMERASE PHI6P2 WITH 6NT RNA

Molecular Description:

RNA-DEPENDENT RNA POLYMERASE

Deposited:

2004-01-21

Released:

2004-02-19

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Salgado, P.S., Makeyev, E.V., Butcher, S.J., Bamford, D.H., Stuart, D.I., Grimes, J.M.
The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase. 
Structure, 12, pp. 307 - 316, 2004.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 105.13   b = 93.711   c = 140.741 (Ångstroms)

α = 90.0   β = 101.22   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.23 for 142476 reflections in the resolution range 19.93 to 2.15 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)