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NDB ID: NA0318    PDB ID: 2VBO 


Title:

MOLECULAR BASIS OF HUMAN XPC GENE RECOGNITION AND CLEAVAGE BY ENGINEERED HOMING ENDONUCLEASE HETERODIMERS

Molecular Description:

DNA ENDONUCLEASE I-CREI (E.C.3.1.-.-)

Deposited:

2007-09-14

Released:

2008-10-28

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Redondo, P., Prieto, J., Munoz, I.G., Alibes, A., Stricher, F., Serrano, L., Cabaniols, J.P., Daboussi, F., Arnould, S., Perez, C., Duchateau, P., Paques, F., Blanco, F.J., Montoya, G.
Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases 
Nature, 456, pp. 107 - , 2008.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 45.993   b = 67.95   c = 76.629 (Ångstroms)

α = 90.0   β = 90.1   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.153 for 41668 reflections in the resolution range 39.47 to 1.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)