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NDB ID: NA0377    PDB ID: 3KS8 


Title:

CRYSTAL STRUCTURE OF RESTON EBOLAVIRUS VP35 RNA BINDING DOMAIN IN COMPLEX WITH 18BP DSRNA

Molecular Description:

Polymerase cofactor VP35/RNA Complex

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Kimberlin, C.R., Bornholdt, Z.A., Li, S., Woods, V.L., Macrae, I.J., Saphire, E.O.
Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression. 
Proc.Natl.Acad.Sci.USA, 107, pp. 314 - 319, 2009.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31

Cell Constants:

a = 85.685   b = 85.685   c = 108.812 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine: dev_222) program. The R value is 0.2 for 29669 reflections in the resolution range 35.117 to 2.401 Ångstroms with Fobs >  1.96 sigma(Fobs) and with I >  0.0 sigma(I)