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NDB ID: NA0403    PDB ID: 3KYL 


Title:

STRUCTURE OF THE CATALYTIC SUBUNIT OF TELOMERASE BOUND TO ITS RNA TEMPLATE AND TELOMERIC DNA

Molecular Description:

Telomerase reverse transcriptase/DNA/RNA complex

Deposited:

2009-12-06

Released:

2010-03-31

Structural Keywords:

A DOUBLE HELIX, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Mitchell, M., Gillis, A., Futahashi, M., Fujiwara, H., Skordalakes, E.
Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA. 
Nat.Struct.Mol.Biol., 17, pp. 513 - 518, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 77.231   b = 52.782   c = 101.609 (Ångstroms)

α = 90.0   β = 101.9   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.24456 for 19815 reflections in the resolution range 25.51 to 2.7 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)