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NDB ID: NA0405    PDB ID: 3KTU 


Title:

STRUCTURE OF HUMAN 8-OXOGUANINE GLYCOSYLASE 1 BOUND TO FLUORNINATED OXOG-CONTAINING DNA

Molecular Description:

N-glycosylase/DNA lyase (E.C.3.2.2.-
4.2.99.18)/DNA complex

Deposited:

2009-11-26

Released:

2010-07-14

Structural Keywords:

B DOUBLE HELIX, FLIPPED-OUT BASES, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Verdine, G.L., Lee, S.M.
Structural investigation of hOGG1 bound to a fluorinated oxoG analog
to be published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 92.4   b = 92.4   c = 212.5 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.225 for 23379 reflections in the resolution range 25.21 to 2.3 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)