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NDB ID: NA0463    PDB ID: 3LWP 


Title:

STRUCTURE OF H/ACA RNP BOUND TO A SUBSTRATE RNA CONTAINING 5BRDU

Molecular Description:

Probable tRNA pseudouridine synthase B (E.C.5.4.99.-)
Ribosome biogenesis protein Nop10
50S ribosomal protein L7Ae/RNA complex

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

Zhou, J., Liang, B., Lv, C., Yang, W., Li, H.
Glycosidic Bond Conformation Preference Plays a Pivotal Role in Catalysis of RNA Pseudouridylation: A Combined Simulation and Structural Study
J.Mol.Biol., , pp. - , 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 188.173   b = 64.58   c = 83.798 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine) program. The R value is 0.2061 for 35135 reflections in the resolution range 34.841 to 2.5 Ångstroms with Fobs >  1.89 sigma(Fobs) and with I >  0.0 sigma(I)