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NDB ID: NA0465    PDB ID: 3LWR 


Title:

STRUCTURE OF H/ACA RNP BOUND TO A SUBSTRATE RNA CONTAINING 4SU

Molecular Description:

Pseudouridine synthase Cbf5 (E.C.5.4.99.-)
Ribosome biogenesis protein Nop10
50S ribosomal protein L7Ae/RNA complex

Structural Keywords:

DOUBLE HELIX, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

Zhou, J., Liang, B., Li, H.
Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase . 
Biochemistry, 49, pp. 6276 - 6281, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 187.355   b = 64.434   c = 83.388 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2234 for 51603 reflections in the resolution range 41.694 to 2.203 Ångstroms with Fobs >  1.89 sigma(Fobs) and with I >  0.0 sigma(I)