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NDB ID: NA0468    PDB ID: 3LRR 


Title:

CRYSTAL STRUCTURE OF HUMAN RIG-I CTD BOUND TO A 12 BP AU RICH 5' PPP DSRNA

Molecular Description:

Probable ATP-dependent RNA helicase DDX58 (E.C.3.6.1.-)

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Lu, C., Xu, H., Ranjith-Kumar, C.T., Brooks, M.T., Hou, T.Y., Hu, F., Herr, A.B., Strong, R.K., Kao, C.C., Li, P.
The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain. 
Structure, 18, pp. 1032 - 1043, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65

Cell Constants:

a = 83.01   b = 83.01   c = 111.22 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the CNS 1.1 program. The R value is 0.187 for 20357 reflections in the resolution range 30.19 to 2.15 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)