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NDB ID: NA0470    PDB ID: 3LWM 


Title:

STRUCTURE OF THE LARGE FRAGMENT OF THERMUS AQUATICUS DNA POLYMERASE I IN COMPLEX WITH A BLUNT-ENDED DNA AND DDATP

Molecular Description:

DNA polymerase I
thermostable (E.C.2.7.7.7)/DNA complex

Deposited:

2010-02-24

Released:

2010-05-05

Structural Keywords:

B DOUBLE HELIX, FLIPPED-OUT BASES, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Obeid, S., Blatter, N., Kranaster, R., Schnur, A., Diederichs, K., Welte, W., Marx, A.
Replication through an abasic DNA lesion: structural basis for adenine selectivity 
Embo J., 29, pp. 1738 - 1747, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 2 1

Cell Constants:

a = 109.592   b = 109.592   c = 91.037 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1857 for 32553 reflections in the resolution range 47.455 to 2.186 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  -3.0 sigma(I)