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NDB ID: NA0483    PDB ID: 2WTF 


Title:

DNA POLYMERASE ETA IN COMPLEX WITH THE CIS-DIAMMINEPLATINUM (II) 1,3- GTG INTRASTRAND CROSS-LINK

Molecular Description:

DNA POLYMERASE ETA (E.C.2.7.7.7)

Deposited:

2009-09-16

Released:

2010-03-31

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Reissner, T., Schneider, S., Schorr, S., Carell, T.
Crystal Structure of a Cisplatin-(1,3-Gtg) Cross-Link within DNA Polymerase Eta. 
Angew.Chem.Int.Ed.Engl., 49, pp. 3077 - , 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 103.24   b = 103.24   c = 292.74 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.22922 for 52206 reflections in the resolution range 48.0 to 2.5 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)