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NDB ID: NA0485    PDB ID: 3M9E 


Title:

THYROID HORMONE BETA DNA BINDING DOMAIN HOMODIMER WITH INVERTED PALINDROME TRE

Molecular Description:

Thyroid hormone receptor beta

Deposited:

2010-03-22

Released:

2010-08-18

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Chen, Y., Young, M.A.
Structure of a thyroid hormone receptor DNA-binding domain homodimer bound to an inverted palindrome DNA response element. 
Mol.Endocrinol., 24, pp. 1650 - 1664, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 73.738   b = 83.468   c = 75.743 (Ångstroms)

α = 90.0   β = 98.28   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1819 for 34766 reflections in the resolution range 42.182 to 2.406 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)