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NDB ID: NA0552    PDB ID: 3MUT 


Title:

CRYSTAL STRUCTURE OF THE G20A/C92U MUTANT C-DI-GMP RIBOSWITH BOUND TO C-DI-GMP

Molecular Description:

U1 small nuclear ribonucleoprotein A/RNA COMPLEX

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Smith, K.D., Lipchock, S.V., Livingston, A.L., Shanahan, C.A., Strobel, S.A.
Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch . 
Biochemistry, 49, pp. 7351 - 7359, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 49.69   b = 45.43   c = 78.93 (Ångstroms)

α = 90.0   β = 95.12   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.5.0102 program. The R value is 0.23435 for 6354 reflections in the resolution range 49.49 to 3.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)