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NDB ID: NA0553    PDB ID: 3MUV 


Title:

CRYSTAL STRUCTURE OF THE G20A/C92U MUTANT C-DI-GMP RIBOSWITH BOUND TO C-DI-AMP

Molecular Description:

U1 small nuclear ribonucleoprotein A/RNA complex

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Smith, K.D., Lipchock, S.V., Livingston, A.L., Shanahan, C.A., Strobel, S.A.
Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch . 
Biochemistry, 49, pp. 7351 - 7359, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 48.87   b = 45.898   c = 75.696 (Ångstroms)

α = 90.0   β = 95.48   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.5.0102 program. The R value is 0.19 for 4829 reflections in the resolution range 48.65 to 3.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)