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NDB ID: NA0600    PDB ID: 3NHG 


Title:

RB69 DNA POLYMERASE (S565G/Y567A) TERNARY COMPLEX WITH DTTP OPPOSITE DG

Molecular Description:

DNA polymerase (E.C.2.7.7.7)/DNA complex

Deposited:

2010-06-14

Released:

2011-01-26

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Xia, S., Wang, M., Lee, H.R., Sinha, A., Blaha, G., Christian, T., Wang, J., Konigsberg, W.
Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures. 
J.Mol.Biol., 406, pp. 558 - 570, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 75.052   b = 119.999   c = 130.382 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.18848 for 37719 reflections in the resolution range 50.0 to 2.5 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)