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NDB ID: NA0601    PDB ID: 3NCU 


Title:

STRUCTURAL AND FUNCTIONAL INSIGHTS INTO PATTERN RECOGNITION BY THE INNATE IMMUNE RECEPTOR RIG-I

Molecular Description:

RIG-I (E.C.3.6.1.-)/RNA complex

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Wang, Y., Ludwig, J., Schuberth, C., Goldeck, M., Schlee, M., Li, H., Juranek, S., Sheng, G., Micura, R., Tusch, T., Hartmann, G., Patel, D.
Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I
Nat.Struct.Mol.Biol., , pp. - , 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65

Cell Constants:

a = 83.462   b = 83.462   c = 110.364 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine: 1.6.1_357) program. The R value is 0.1921 for 14204 reflections in the resolution range 39.034 to 2.55 Ångstroms with Fobs >  0.2 sigma(Fobs) and with I >  0.0 sigma(I)