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NDB ID: NA0698    PDB ID: 3OHA     NAKB(beta): NA0698 


Title:

YEAST DNA POLYMERASE ETA INSERTING DCTP OPPOSITE AN 8OXOG LESION

Molecular Description:

DNA polymerase eta (E.C.2.7.7.7)/DNA complex

Deposited:

2010-08-17

Released:

2010-12-22

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Silverstein, T.D., Jain, R., Johnson, R.E., Prakash, L., Prakash, S., Aggarwal, A.K.
Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta. 
Structure, 18, pp. 1463 - 1470, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 88.039   b = 227.635   c = 86.077 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.15928 for 55839 reflections in the resolution range 34.82 to 2.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)