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NDB ID: NA0707    PDB ID: 3OLB 


Title:

POLIOVIRUS POLYMERASE ELONGATION COMPLEX WITH 2',3'-DIDEOXY-CTP

Molecular Description:

Polyprotein (E.C.2.7.7.48)/RNA complex

Structural Keywords:

DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Gong, P., Peersen, O.B.
Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase. 
Proc.Natl.Acad.Sci.USA, 107, pp. 22505 - 22510, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 60.528   b = 60.539   c = 192.936 (Ångstroms)

α = 83.82   β = 83.84   γ = 77.35 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine: 1.6.4_486) program. The R value is 0.2196 for 98983 reflections in the resolution range 45.226 to 2.41 Ångstroms with Fobs >  2.06 sigma(Fobs) and with I >  0.0 sigma(I)