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NDB ID: NA0780    PDB ID: 3OY9 


Title:

CRYSTAL STRUCTURE OF THE PROTOTYPE FOAMY VIRUS (PFV) INTASOME IN COMPLEX WITH MANGANESE AT 2.55 RESOLUTION

Molecular Description:

PFV integrase

Deposited:

2010-09-23

Released:

2010-10-20

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hare, S., Gupta, S.S., Valkov, E., Engelman, A., Cherepanov, P.
Retroviral intasome assembly and inhibition of DNA strand transfer. 
Nature, 464, pp. 232 - 236, 2010.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 160.09   b = 160.09   c = 123.94 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.1986 for 52062 reflections in the resolution range 39.21 to 2.55 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)