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NDB ID: NA0811    PDB ID: 3P4C 


Title:

ALTERNATINGLY MODIFIED 2'FLUORO RNA OCTAMER F/RA2U2-R32

Molecular Description:

5'-R(*(CFZ)P*GP*(AF2)P*AP*(UFT)P*UP*(CFZ)P*G)-3'

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Pallan, P.S., Greene, E.M., Jicman, P.A., Pandey, R.K., Manoharan, M., Rozners, E., Egli, M.
Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA. 
Nucleic Acids Res., 39, pp. 3482 - 3495, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

H 3 2

Cell Constants:

a = 40.55   b = 40.55   c = 117.222 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the SHELXL-97 program. The R value is 0.182 for 13314 reflections in the resolution range 50.0 to 1.15 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)