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NDB ID: NA0837    PDB ID: 3PMN 


Title:

TERNARY CRYSTAL STRUCTURE OF POLYMERASE LAMBDA VARIANT WITH A GT MISPAIR AT THE PRIMER TERMINUS WITH MN2+ IN THE ACTIVE SITE

Molecular Description:

DNA polymerase lambda (E.C.2.7.7.7
4.2.99.-)/DNA complex

Deposited:

2010-11-17

Released:

2011-02-02

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Bebenek, K., Pedersen, L.C., Kunkel, T.A.
Replication infidelity via a mismatch with Watson-Crick geometry. 
Proc.Natl.Acad.Sci.USA, 108, pp. 1862 - 1867, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 56.39   b = 62.417   c = 139.881 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.213 for 22799 reflections in the resolution range 25.27 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)