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NDB ID: NA0870    PDB ID: 3PZP 


Title:

HUMAN DNA POLYMERASE KAPPA EXTENDING OPPOSITE A CIS-SYN THYMINE DIMER

Molecular Description:

DNA polymerase kappa (E.C.2.7.7.7)/DNA Complex

Deposited:

2010-12-14

Released:

2011-12-28

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Vasquez-Del Carpio, R., Silverstein, T.D., Lone, S., Johnson, R.E., Prakash, L., Prakash, S., Aggarwal, A.K.
Role of human DNA polymerase kappa in extension opposite from a cis-syn thymine dimer. 
J.Mol.Biol., 408, pp. 252 - 261, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 117.136   b = 154.476   c = 217.854 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.24389 for 27432 reflections in the resolution range 46.67 to 3.336 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)