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NDB ID: NA0903    PDB ID: 3Q0D 


Title:

CRYSTAL STRUCTURE OF SUVH5 SRA- HEMI METHYLATED CG DNA COMPLEX

Molecular Description:

Histone-lysine N-methyltransferase
H3 lysine-9 specific SUVH5 (E.C.2.1.1.43)

Deposited:

2010-12-15

Released:

2011-02-23

Structural Keywords:

B DOUBLE HELIX, INTERNAL LOOP

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Rajakumara, E., Law, J.A., Simanshu, D.K., Voigt, P., Johnson, L.M., Reinberg, D., Patel, D.J., Jacobsen, S.E.
A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo. 
Genes Dev., 25, pp. 137 - 152, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 42

Cell Constants:

a = 76.379   b = 76.379   c = 74.254 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2265 for 17221 reflections in the resolution range 19.095 to 2.3704 Ångstroms with Fobs >  1.39 sigma(Fobs) and with I >  0.0 sigma(I)