A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 3-Mar-2021 number of released structures: 11234
Search for released structures

NDB ID: NA0971    PDB ID: 3QRF 


Title:

STRUCTURE OF A DOMAIN-SWAPPED FOXP3 DIMER

Molecular Description:

Nuclear factor of activated T-cells
cytoplasmic 2
Forkhead box protein P3/DNA complex

Deposited:

2011-02-17

Released:

2011-04-20

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Bandukwala, H.S., Wu, Y., Feuerer, M., Chen, Y., Barboza, B., Ghosh, S., Stroud, J.C., Benoist, C., Mathis, D., Rao, A., Chen, L.
Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells. 
Immunity, 34, pp. 479 - 491, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 83.667   b = 131.234   c = 68.665 (Ångstroms)

α = 90.0   β = 89.95   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.0 for 35150 reflections in the resolution range 50.0 to 2.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)